The American University in Cairo's Office of Athletics sponsors 29 Men's sports under the supervision of the Egyptian Universities Sports Federation. These sports are:
- Basketball
- Football
- Futsal
- Handball
- Squash
- Swimming
- Indoor Rowing
- Tennis
- Track and Field
- Volleyball
- Water Polo
- Pentathlon
- Fencing
- Table Tennis
- Cycling
- Karate
- Darts
- Cross Fit
- Speed Ball
- Badminton
- Billiard
- Taekwondo
- Judo
- Orienteering
- Gymnastics
- Weight Lifting
- Archery
- Chess
- E Games
AUC's competitive teams compete on a national level every year in tournaments sponsored by the Egyptian Universities Sports Federation (EUSF). The Office of Athletics also organizes trips for teams to compete with other universities in Egypt and abroad, as well as sports days with colleges, clubs, and other institutions in Egypt and abroad.